Treatment of iron deficiency and iron deficiency anemia: latent or overt iron deficiency anemia in children and adults, secondary to chronic blood loss, pregnancy; breast-feeding.

• Adults: 1 to 2 vials a day (equivalent to 40-80 mg of Fe3+), in 2 administrations, preferably before food.
• Children: Take 1.5 ml/kg/die from a vial (equivalent to 4 mg/kg/die of Fe3+), in 2 administrations, preferably before food.
• Drink the solution out of the vial or dilute it in natural water.
• Duration of treatment: the treatment must be carried on until total recovery of normal iron stores (usually for 2-3 months).
• Maximum daily dose: clinical trials on the product effectiveness and tolerability were made administering the product at the above specified dosage levels (adults: 1600 mg/day - Children: 1.5 of ml/kg/day of iron proteinsuccinylate); no data about clinical efficacy and tolerability of higher dosages of the product are available.

• No particular warnings are required about risks of tolerance or addiction.
• The treatment should not exceed 6 months, unless in case of persisting bleeding, menorrhagia or pregnancy.
• Any disease possibly underlying iron deficiency or iron deficiency anemia must be ascertained and properly treated.
• As the product contains milk proteins, it must be used with caution in patients suffering from milk-protein intolerance, who may have allergic reactions.
• Ferplex vials contain sorbitol, therefore patients with rare hereditary fructose intolerance must not take this medicine.
• Ferplex vials contain parabens (methyl-p-hydroxybenzoate sodium salt, propyl-p-hydroxybenzoate sodium salt) that may cause delayed allergic reactions.